'In Great Distress' in the Bible

saying, "My servant, sir, is lying sick with paralysis at my house, in great distress."

And, taking with him, Peter and the two sons of Zebedee, he began to be grieved and to be in great distress.

And he taketh Peter and James and John with him, and began to be exceedingly amazed, and in great distress;

His parents were amazed when they saw him, and his mother said to him: "My child, why have you treated us like this? Your father and I have been searching for you in great distress."

Since he hath been longing to see, you all, and hath been in great distress, because ye had heard he was sick; -