'Misery' in the Bible

"Look, you are pregnant and will give birth to a son," the angel of the LORD continued to say to her. "You will name him Ishmael, because the LORD has heard your cry of misery.

Then Leah conceived and gave birth to a son, and she called his name Reuben, for she said, "Because Yahweh has noticed my misery, that I [am] unloved. Now my husband will love me."

If the God of my father the God of Abraham, the God whom Isaac feared had not been with me, you would have sent me away empty handed. But God saw my misery and how hard I've worked with my own hands and he rebuked you last night."

And if ye take this one also from me, and mischief should befall him, ye will bring down my grey hairs with misery to Sheol.

For how can I go up to my father if the boy is not with me? {I do not want to see} the misery which will find my father."