'Anguished' in the Bible

My servants will shout for joy from a glad heart,but you will cry out from an anguished heart,and you will lament out of a broken spirit.

Indeed, at the ascent of Luhith people will go up with bitter weeping. At the descent of Horonaim the anguished cries over the destruction will be heard.

Give them an anguished heart; may your curse be upon them!

He took with him Peter and the two sons of Zebedee, and became anguished and distressed.

For I wrote to you with many tears out of an extremely troubled and anguished heart—not that you should be hurt, but that you should know the abundant love I have for you.