Mark 10:6

But from the beginning of creation God made them male and female.

Genesis 1:27

So God created man in His own image, in the image and likeness of God He created him; male and female He created them.

Genesis 5:2

He created them male and female, and blessed them and named them Mankind at the time they were created.

2 Peter 3:4

and saying, “Where is the promise of His coming [what has become of it]? For ever since the fathers fell asleep [in death], all things have continued [exactly] as they did from the beginning of creation.”

Genesis 1:1

In the beginning God (Elohim) created [by forming from nothing] the heavens and the earth.

Genesis 2:20-23

And the man gave names to all the livestock, and to the birds of the air, and to every animal of the field; but for Adam there was not found a helper [that was] suitable (a companion) for him.

Malachi 2:14-16

But you say, “Why [does He reject it]?” Because the Lord has been a witness between you and the wife of your youth, against whom you have dealt treacherously. Yet she is your marriage companion and the wife of your covenant [made by your vows].

Mark 13:19

for at that time there will be such tribulation as has not occurred, from the beginning of the creation which God made, until now—and never will [be again].

Treasury of Scripture Knowledge

Summary

But from the beginning of the creation God made them male and female.

The beginning

Bible References

The beginning

Genesis 1:1
In the beginning God (Elohim) created [by forming from nothing] the heavens and the earth.
2 Peter 3:4
and saying, “Where is the promise of His coming [what has become of it]? For ever since the fathers fell asleep [in death], all things have continued [exactly] as they did from the beginning of creation.”

God

Genesis 1:27
So God created man in His own image, in the image and likeness of God He created him; male and female He created them.
Genesis 2:20
And the man gave names to all the livestock, and to the birds of the air, and to every animal of the field; but for Adam there was not found a helper [that was] suitable (a companion) for him.
Genesis 5:2
He created them male and female, and blessed them and named them Mankind at the time they were created.
Malachi 2:14
But you say, “Why [does He reject it]?” Because the Lord has been a witness between you and the wife of your youth, against whom you have dealt treacherously. Yet she is your marriage companion and the wife of your covenant [made by your vows].