'Great Distress' in the Bible

for that will be 'a time of great distress, the like of which has not occurred from the beginning of the world down to the present time'--no, nor ever will again.

His parents were amazed when they saw him, and his mother said to him: "My child, why have you treated us like this? Your father and I have been searching for you in great distress."

Then a famine spread over the whole of Egypt and Canaan, causing great distress, and our ancestors could find no food.